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A technology designed to preserve synapses across the whole brain of a large mammal is successful Using a combination of ultrafast glutaraldehyde fixation and very low temperature storage, [...]

Let’s imagine that in a hypothetical future world, head transplants become possible, as somehow the massive technical challenge of reattaching the brain to the spinal cord can be overcome. [...]

A new manuscript from Gornet et al. describes their work using a serial electron micrograph-derived Drosophila connectome to simulate motion-detection in neurons in the T4 area of the optic lobe: [...]

In cryobiology, it is generally thought that cellular gene expression profiles do not change substantially following cryopreservation. This is important because if viability cannot be directly [...]

A manuscript by Manuchehrabadi et al. about using magnetic nanoparticles to improve rewarming of vitrified tissue samples made quite a splash when it was published earlier this month. What is the [...]

It is sometimes claimed that it is impossible for people without strong wet-lab skills in biology and/or neuroscience to personally contribute to research associated with brain preservation. As [...]

The Less Wrong (LW) extended community — an internet community interested in the application of rational thinking — recently conducted a survey of their members, thanks in part to the [...]

One of the key questions that I’ve had following the publication and success of aldehyde stabilized cryopreservation at mouse brain preservation is the degree to which the glutaraldehyde [...]

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Although most people usually focus on the brain cells when discussing brain preservation techniques, extracellular space is also worthy of consideration. In vivo, extracellular space makes up [...]